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Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy

Mutations in the cardiac actin gene (ACTC1) are associated with the development of hypertrophic cardiomyopathy (HCM). To date, 12 different ACTC1 mutations have been discovered in patients with HCM. Given the high degree of sequence conservation of actin proteins and the range of protein–protein int...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Despond, Evan A., Dawson, John F.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913282/
https://ncbi.nlm.nih.gov/pubmed/29719515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00405
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