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Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy

Mutations in the cardiac actin gene (ACTC1) are associated with the development of hypertrophic cardiomyopathy (HCM). To date, 12 different ACTC1 mutations have been discovered in patients with HCM. Given the high degree of sequence conservation of actin proteins and the range of protein–protein int...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Despond, Evan A., Dawson, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913282/
https://ncbi.nlm.nih.gov/pubmed/29719515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00405
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