The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation

Interleukin 33 (IL-33) is among the earliest-released cytokines in response to allergens that orchestrate type 2 immunity. The prolyl cis-trans isomerase PIN1 is known to induce cytokines for eosinophil survival and activation by stabilizing cytokines mRNAs, but the function of PIN1 in upstream sign...

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Udgivet i:Nat Commun
Main Authors: Nechama, Morris, Kwon, Jeahoo, Wei, Shuo, Tun-Kyi, Adrian, Welner, Robert S., Ben-Dov, Iddo Z., Arredouani, Mohamed S., Asara, John M., Chen, Chun-Hau, Tsai, Cheng-Yu, Nelson, Kyle F., Kobayashi, Koichi S, Israel, Elliot, Zhou, Xiao Zhen, Nicholson, Linda K., Lu, Kun Ping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913134/
https://ncbi.nlm.nih.gov/pubmed/29686383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03886-6
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