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Can the combination of hyperthermia, seizures and ion channel dysfunction cause fatal post-ictal cerebral edema in patients with SCN1A mutations?

A 21-year-old male with an SCN1A mutation died of cerebral herniation 3 h after a seizure occurring during physical activity. Cases of fatal cerebral edema in patients with SCN1A mutations after fever and status epilepticus have been recently reported raising the question whether sodium channel dysf...

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Detalhes bibliográficos
Publicado no:Epilepsy Behav Case Rep
Main Authors: Büren, Carina, Kamp, Marcel Alexander, Munoz-Bendix, Christopher, Steiger, Hans-Jakob, Windolf, Joachim, Dibué-Adjei, Maxine
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913039/
https://ncbi.nlm.nih.gov/pubmed/29692967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebcr.2017.12.003
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