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Can the combination of hyperthermia, seizures and ion channel dysfunction cause fatal post-ictal cerebral edema in patients with SCN1A mutations?

A 21-year-old male with an SCN1A mutation died of cerebral herniation 3 h after a seizure occurring during physical activity. Cases of fatal cerebral edema in patients with SCN1A mutations after fever and status epilepticus have been recently reported raising the question whether sodium channel dysf...

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Bibliografiske detaljer
Udgivet i:Epilepsy Behav Case Rep
Main Authors: Büren, Carina, Kamp, Marcel Alexander, Munoz-Bendix, Christopher, Steiger, Hans-Jakob, Windolf, Joachim, Dibué-Adjei, Maxine
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913039/
https://ncbi.nlm.nih.gov/pubmed/29692967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebcr.2017.12.003
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