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Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol

Controlled distribution of lipids across various cell membranes is crucial for cell homeostasis and regulation. We developed an imaging method that allows simultaneous in situ quantification of cholesterol in two leaflets of the plasma membrane (PM) using tunable orthogonal cholesterol sensors. Our...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Liu, Shu-Lin, Sheng, Ren, Jung, Jae Hun, Wang, Li, Stec, Ewa, O’Connor, Matthew J, Song, Seohyoen, Bikkavilli, Rama Kamesh, Winn, Robert A, Lee, Daesung, Baek, Kwanghee, Ueda, Kazumitsu, Levitan, Irena, Kim, Kwang-Pyo, Cho, Wonhwa
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912897/
https://ncbi.nlm.nih.gov/pubmed/28024150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2268
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