In vivo insertion pool sequencing identifies virulence factors in a complex fungal–host interaction

Large-scale insertional mutagenesis screens can be powerful genome-wide tools if they are streamlined with efficient downstream analysis, which is a serious bottleneck in complex biological systems. A major impediment to the success of next-generation sequencing (NGS)-based screens for virulence fac...

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Bibliographic Details
Published in:PLoS Biol
Main Authors: Uhse, Simon, Pflug, Florian G., Stirnberg, Alexandra, Ehrlinger, Klaus, von Haeseler, Arndt, Djamei, Armin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Methods and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912717/
https://ncbi.nlm.nih.gov/pubmed/29684023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005129
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