Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh

BACKGROUND: The mediators of protection against cholera, a severe dehydrating illness of humans caused by Vibrio cholerae, are unknown. We have previously shown that plasma IgA as well as memory B IgG cells targeting lipopolysaccharide (LPS) of Vibrio cholerae O1 correlate with protection against V....

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Bibliografiska uppgifter
I publikationen:PLoS Negl Trop Dis
Huvudupphovsmän: Aktar, Amena, Rahman, M. Arifur, Afrin, Sadia, Akter, Aklima, Uddin, Taher, Yasmin, Tahirah, Sami, Md. Israk Nur, Dash, Pinki, Jahan, Sultana Rownok, Chowdhury, Fahima, Khan, Ashraful I., LaRocque, Regina C., Charles, Richelle C., Bhuiyan, Taufiqur Rahman, Mandlik, Anjali, Kelly, Meagan, Kováč, Pavol, Xu, Peng, Calderwood, Stephen B., Harris, Jason B., Qadri, Firdausi, Ryan, Edward T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912711/
https://ncbi.nlm.nih.gov/pubmed/29684006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006399
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