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Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh

BACKGROUND: The mediators of protection against cholera, a severe dehydrating illness of humans caused by Vibrio cholerae, are unknown. We have previously shown that plasma IgA as well as memory B IgG cells targeting lipopolysaccharide (LPS) of Vibrio cholerae O1 correlate with protection against V....

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Wydane w:PLoS Negl Trop Dis
Główni autorzy: Aktar, Amena, Rahman, M. Arifur, Afrin, Sadia, Akter, Aklima, Uddin, Taher, Yasmin, Tahirah, Sami, Md. Israk Nur, Dash, Pinki, Jahan, Sultana Rownok, Chowdhury, Fahima, Khan, Ashraful I., LaRocque, Regina C., Charles, Richelle C., Bhuiyan, Taufiqur Rahman, Mandlik, Anjali, Kelly, Meagan, Kováč, Pavol, Xu, Peng, Calderwood, Stephen B., Harris, Jason B., Qadri, Firdausi, Ryan, Edward T.
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2018
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Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912711/
https://ncbi.nlm.nih.gov/pubmed/29684006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006399
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