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Covalent Binding of the Benzamide RH-4032 to Tubulin in Suspension-Cultured Tobacco Cells and Its Application in a Cell-Based Competitive-Binding Assay

The benzamide, RH-4032, was found to be a potent antimicrotubule agent in tobacco (Nicotiana tabacum) cells. It strongly inhibited root growth and produced swollen club-shaped roots, an accumulation of cells in arrested metaphase, and loss of microtubules. RH-4032 inhibited the in vitro assembly of...

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Detalhes bibliográficos
Main Authors: Young, David H., Lewandowski, Veronica T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Physiologists 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC59127/
https://ncbi.nlm.nih.gov/pubmed/10982427
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