Covalent Binding to Tubulin by Isothiocyanates: A MECHANISM OF CELL GROWTH ARREST AND APOPTOSIS

Isothiocyanates (ITCs) found in cruciferous vegetables, including benzyl-ITC (BITC), phenethyl-ITC (PEITC), and sulforaphane (SFN), inhibit carcinogenesis in animal models and induce apoptosis and cell cycle arrest in various cell types. The biochemical mechanisms of cell growth inhibition by ITCs a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mi, Lixin, Xiao, Zhen, Hood, Brian L., Dakshanamurthy, Sivanesan, Wang, Xiantao, Govind, Sudha, Conrads, Thomas P., Veenstra, Timothy D., Chung, Fung-Lung
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Molecular Basis of Cell and Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494917/
https://ncbi.nlm.nih.gov/pubmed/18524779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802330200
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