Covalent Binding to Tubulin by Isothiocyanates: A MECHANISM OF CELL GROWTH ARREST AND APOPTOSIS

Isothiocyanates (ITCs) found in cruciferous vegetables, including benzyl-ITC (BITC), phenethyl-ITC (PEITC), and sulforaphane (SFN), inhibit carcinogenesis in animal models and induce apoptosis and cell cycle arrest in various cell types. The biochemical mechanisms of cell growth inhibition by ITCs a...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Mi, Lixin, Xiao, Zhen, Hood, Brian L., Dakshanamurthy, Sivanesan, Wang, Xiantao, Govind, Sudha, Conrads, Thomas P., Veenstra, Timothy D., Chung, Fung-Lung
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2008
נושאים:
Molecular Basis of Cell and Developmental Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494917/
https://ncbi.nlm.nih.gov/pubmed/18524779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802330200
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