Covalent Binding to Tubulin by Isothiocyanates: A MECHANISM OF CELL GROWTH ARREST AND APOPTOSIS

Isothiocyanates (ITCs) found in cruciferous vegetables, including benzyl-ITC (BITC), phenethyl-ITC (PEITC), and sulforaphane (SFN), inhibit carcinogenesis in animal models and induce apoptosis and cell cycle arrest in various cell types. The biochemical mechanisms of cell growth inhibition by ITCs a...

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Xehetasun bibliografikoak
Egile Nagusiak: Mi, Lixin, Xiao, Zhen, Hood, Brian L., Dakshanamurthy, Sivanesan, Wang, Xiantao, Govind, Sudha, Conrads, Thomas P., Veenstra, Timothy D., Chung, Fung-Lung
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Molecular Basis of Cell and Developmental Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494917/
https://ncbi.nlm.nih.gov/pubmed/18524779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802330200
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