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Functional roles of the DNA-binding HMGB domain in the histone chaperone FACT in nucleosome reorganization
The essential histone chaperone FACT (facilitates chromatin transcription) promotes both nucleosome assembly and disassembly. FACT is a heterodimer of Spt16 with either SSRP1 or Pob3, differing primarily by the presence of a high-mobility group B (HMGB) DNA-binding domain furnished only by SSRP1. Ye...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5912460/ https://ncbi.nlm.nih.gov/pubmed/29514976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000199 |
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