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Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood

Monoclonal antibodies (mAbs) are powerful tools useful for both fundamental research and in biomedicine. Their high specificity is indispensable when the antibody needs to distinguish between highly related structures (e.g., a normal protein and a mutated version thereof). The current way of generat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Vis Exp
Prif Awduron: Devilder, Marie-Claire, Moyon, Mélinda, Saulquin, Xavier, Gautreau-Rolland, Laetitia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MyJove Corporation 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912359/
https://ncbi.nlm.nih.gov/pubmed/29443062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56508
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