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Cells on the run: shear regulated integrin activation in leukocyte rolling and arrest on endothelial cells

The arrest of rolling leukocytes on various target vascular beds is mediated by specialized leukocyte integrins and their endothelial immunoglobulin superfamily (IgSF) ligands. These integrins are kept in largely inactive states and undergo in situ activation upon leukocyte-endothelial contact by bo...

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Bibliografische gegevens
Gepubliceerd in:Curr Opin Cell Biol
Hoofdauteurs: Alon, Ronen, Ley, Klaus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912339/
https://ncbi.nlm.nih.gov/pubmed/18499427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.04.003
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