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Cells on the run: shear regulated integrin activation in leukocyte rolling and arrest on endothelial cells

The arrest of rolling leukocytes on various target vascular beds is mediated by specialized leukocyte integrins and their endothelial immunoglobulin superfamily (IgSF) ligands. These integrins are kept in largely inactive states and undergo in situ activation upon leukocyte-endothelial contact by bo...

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Detalhes bibliográficos
Publicado no:Curr Opin Cell Biol
Main Authors: Alon, Ronen, Ley, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912339/
https://ncbi.nlm.nih.gov/pubmed/18499427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.04.003
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