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Nutlin‐3a as a novel anticancer agent for adrenocortical carcinoma with CTNNB1 mutation

Adrenocortical carcinoma (ACC) is a rare malignancy, and CTNNB1 is frequently mutated in ACC. Our study aims to screen for effective agents with antineoplastic activity against ACC with CTNNB1 mutation. In‐silico screening of the Genomics of Drug Sensitivity in Cancer (GDSC) database was conducted....

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Hui, Wen, Liu, Shenghua, Zheng, Jie, Fang, Zujun, Ding, Qiang, Feng, Chenchen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911589/
https://ncbi.nlm.nih.gov/pubmed/29532999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1431
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