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β-Catenin-driven adrenocortical carcinoma is characterized with immune exclusion

AIM: Adrenocortical carcinoma (ACC) is characterized by overexpressed CTNNB1, which is reported to modulate immune exclusion. Cross talk between CTNNB1 and cancer immunity in ACC remains unclear. MATERIALS AND METHODS: In silico reproduction of TCGA-ACC dataset (N = 92) and external validation using...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Liu, Shenghua, Ding, Guanxiong, Zhou, Zhongwen, Feng, Chenchen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898592/
https://ncbi.nlm.nih.gov/pubmed/29670378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S159979
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