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Inducible nitric oxide synthase in innate immune cells is important for restricting cyst formation of Toxoplasma gondii in the brain but not required for the protective immune process to remove the cysts
Significantly larger numbers of Toxoplasma gondii cysts were detected in the brains of RAG1(−/−) NOS2(−/−) than RAG1(−/−) mice following infection. In contrast, the cyst numbers markedly decreased in a same manner in both strains of mice after receiving CD8(+) immune T cells. Thus, NOS2-mediated inn...
Gardado en:
| Publicado en: | Microbes Infect |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5911423/ https://ncbi.nlm.nih.gov/pubmed/29287983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2017.12.004 |
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