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Penetration of CD8(+) Cytotoxic T Cells into Large Target, Tissue Cysts of Toxoplasma gondii, Leads to Its Elimination

CD8(+) cytotoxic T cells kill target cells through direct cell-cell contact. However, it remains unclear how these T cells eliminate a target of large mass. We investigated how CD8(+) T cells remove tissue cysts of Toxoplasma gondii, which can grow to the size of >50 μm in diameter within infecte...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Tiwari, Ashish, Hannah, Rancie, Lutshumba, Jenny, Ochiai, Eri, Weiss, Louis M., Suzuki, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698940/
https://ncbi.nlm.nih.gov/pubmed/31301754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.04.018
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