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Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain

BACKGROUND: Melatonin is a well-known potent endogenous antioxidant pharmacological agent with significant neuroprotective actions. Here in the current study, we explored the nuclear factor erythroid 2-related factor 2 (Nrf2) gene-dependent antioxidant mechanism underlying the neuroprotective effect...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Ali, Tahir, Rehman, Shafiq Ur, Shah, Fawad Ali, Kim, Myeong Ok
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911370/
https://ncbi.nlm.nih.gov/pubmed/29679979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1157-x
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