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The Neurotropic Properties of AAV-PHP.B Are Limited to C57BL/6J Mice
Improved delivery of adeno-associated virus (AAV) vectors to the CNS will greatly enhance their clinical utility. Selection of AAV9 variants in a mouse model led to the isolation of a capsid called PHP.B, which resulted in remarkable transduction of the CNS following intravenous infusion. However, w...
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| Publicado en: | Mol Ther |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5911151/ https://ncbi.nlm.nih.gov/pubmed/29428298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.01.018 |
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