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Direct electrochemical observation of glucosidase activity in isolated single lysosomes from a living cell

The protein activity in individual intracellular compartments in single living cells must be analyzed to obtain an understanding of protein function at subcellular locations. The current methodology for probing activity is often not resolved to the level of an individual compartment, and the results...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Pan, Rongrong, Xu, Mingchen, Burgess, James D., Jiang, Dechen, Chen, Hong-Yuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910846/
https://ncbi.nlm.nih.gov/pubmed/29610324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719844115
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