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Direct electrochemical observation of glucosidase activity in isolated single lysosomes from a living cell

The protein activity in individual intracellular compartments in single living cells must be analyzed to obtain an understanding of protein function at subcellular locations. The current methodology for probing activity is often not resolved to the level of an individual compartment, and the results...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Pan, Rongrong, Xu, Mingchen, Burgess, James D., Jiang, Dechen, Chen, Hong-Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910846/
https://ncbi.nlm.nih.gov/pubmed/29610324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719844115
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