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A molecular dynamics simulation study decodes the Zika virus NS5 methyltransferase bound to SAH and RNA analogue

Since 2015, widespread Zika virus outbreaks in Central and South America have caused increases in microcephaly cases, and this acute problem requires urgent attention. We employed molecular dynamics and Gaussian accelerated molecular dynamics techniques to investigate the structure of Zika NS5 prote...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chuang, Chih-Hung, Chiou, Shean-jaw, Cheng, Tian-Lu, Wang, Yeng-Tseng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910437/
https://ncbi.nlm.nih.gov/pubmed/29679079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24775-4
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