A Rift Valley fever virus Gn ectodomain-based DNA vaccine induces a partial protection not improved by APC targeting

Rift Valley fever virus, a phlebovirus endemic in Africa, causes serious diseases in ruminants and humans. Due to the high probability of new outbreaks and spread to other continents where competent vectors are present, vaccine development is an urgent priority as no licensed vaccines are available...

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Veröffentlicht in:NPJ Vaccines
Hauptverfasser: Chrun, Tiphany, Lacôte, Sandra, Urien, Céline, Jouneau, Luc, Barc, Céline, Bouguyon, Edwige, Contreras, Vanessa, Ferrier-Rembert, Audrey, Peyrefitte, Christophe N., Busquets, Nuria, Vidal, Enric, Pujols, Joan, Marianneau, Philippe, Schwartz-Cornil, Isabelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910381/
https://ncbi.nlm.nih.gov/pubmed/29707242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0052-x
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