Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma

BACKGROUND: Next-generation sequencing (NGS) studies of matched pairs of primary and metastatic tumors in renal cell carcinoma (RCC) have been limited to small cohorts. OBJECTIVE: To evaluate the discordance in somatic mutations between matched primary and metastatic RCC tumors. DESIGN, SETTING, AND...

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Detalhes bibliográficos
Publicado no:Eur Urol Focus
Main Authors: Becerra, Maria F., Reznik, Ed, Redzematovic, Almedina, Tennenbaum, Daniel M., Kashan, Mahyar, Ghanaat, Mazyar, Casuscelli, Jozefina, Manley, Brandon, Jonsson, Philip, DiNatale, Renzo G., Blum, Kyle A., Durack, Jeremy C., Solomon, Stephen B., Arcila, Maria E., Bourque, Caitlin, Socci, Nick, Carlo, Maria I., Lee, Chung-Han, Voss, Martin H., Feldman, Darren R., Motzer, Robert J., Coleman, Jonathan A., Russo, Paul, Cheng, Emily H., Hakimi, A. Ari, Hsieh, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910293/
https://ncbi.nlm.nih.gov/pubmed/29066084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euf.2017.09.016
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