Characterization and Impact of TERT Promoter Region Mutations on Clinical Outcome in Renal Cell Carcinoma

BACKGROUND: Mutations in the promoter region of the TERT gene have been detected in a variety of cancers. These mutations can potentially lead to unlimited cell divisions and result in poor clinical prognosis. OBJECTIVE: To determine the role and relevance of TERT promoter region mutations in both c...

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Vydáno v:Eur Urol Focus
Hlavní autoři: Casuscelli, Jozefina, Becerra, Maria F., Manley, Brandon J., Zabor, Emily C., Reznik, Ed, Redzematovic, Almedina, Arcila, Maria E., Tennenbaum, Daniel M., Ghanaat, Mazyar, Kashan, Mahyar, Stief, Christian G., Carlo, Maria, Voss, Martin H., Feldman, Darren R., Motzer, Robert J., Chen, Yingbei, Reuter, Victor E., Coleman, Jonathan A., Russo, Paul, Hsieh, James J., Ari Hakimi, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984188/
https://ncbi.nlm.nih.gov/pubmed/28951115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euf.2017.09.008
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