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Incorporation of non-proteinogenic amino acids in class I and II lantibiotics

Lantibiotics are ribosomally synthesized and post-translationally modified peptide natural products that contain thioether crosslinks formed by lanthionine and methyllanthionine residues. They exert potent antimicrobial activity against Gram-positive bacteria. We herein report production of analogue...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Kakkar, Nidhi, Perez, Jessica G., Liu, Wenshe R., Jewett, Michael C., van der Donk, Wilfred A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910287/
https://ncbi.nlm.nih.gov/pubmed/29439566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b01024
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