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Chimeric protein identification of dystrophic, Pierson and other laminin polymerization residues

Laminin polymerization is a key step of basement membrane self-assembly that depends on the binding of the three different N-terminal globular LN domains. Several mutations in the LN domains cause LAMA2-deficient muscular dystrophy and LAMB2-deficient Pierson syndrome. These mutations may affect pol...

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Publicado en:Matrix Biol
Autores principales: McKee, Karen K., Aleksandrova, Maya, Yurchenco, Peter D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910262/
https://ncbi.nlm.nih.gov/pubmed/29408412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2018.01.012
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