Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

Stem cell fate can be influenced by metabolite levels in culture but it is unknown whether physiological variations in metabolite levels in normal tissues regulate stem cell function in vivo. We developed a metabolomics method for analysis of rare cell populations isolated directly from tissues and...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Agathocleous, Michalis, Meacham, Corbin E., Burgess, Rebecca J., Piskounova, Elena, Zhao, Zhiyu, Crane, Genevieve M., Cowin, Brianna L., Bruner, Emily, Murphy, Malea M., Chen, Weina, Spangrude, Gerald J., Hu, Zeping, DeBerardinis, Ralph J., Morrison, Sean J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910063/
https://ncbi.nlm.nih.gov/pubmed/28825709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23876
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker