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Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
Stem cell fate can be influenced by metabolite levels in culture but it is unknown whether physiological variations in metabolite levels in normal tissues regulate stem cell function in vivo. We developed a metabolomics method for analysis of rare cell populations isolated directly from tissues and...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5910063/ https://ncbi.nlm.nih.gov/pubmed/28825709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23876 |
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