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An Essential Role for ECSIT in Mitochondrial Complex I Assembly and Mitophagy in Macrophages
ECSIT is a mitochondrial complex I (CI)-associated protein that has been shown to regulate the production of mitochondrial reactive oxygen species (mROS) following engagement of Toll-like receptors (TLRs). We have generated an Ecsit conditional knockout (CKO) mouse strain to study the in vivo role o...
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| Publicado en: | Cell Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5909989/ https://ncbi.nlm.nih.gov/pubmed/29514094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.051 |
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