Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly

The emergence of small open reading frame (sORF)-encoded peptides (SEPs) is rapidly expanding the known proteome at the lower end of the size distribution. Here, we show that the mitochondrial proteome, particularly the respiratory chain, is enriched for small proteins. Using a prediction and valida...

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Vydáno v:Nat Commun
Hlavní autoři: Zhang, Shan, Reljić, Boris, Liang, Chao, Kerouanton, Baptiste, Francisco, Joel Celio, Peh, Jih Hou, Mary, Camille, Jagannathan, Narendra Suhas, Olexiouk, Volodimir, Tang, Claire, Fidelito, Gio, Nama, Srikanth, Cheng, Ruey-Kuang, Wee, Caroline Lei, Wang, Loo Chien, Duek Roggli, Paula, Sampath, Prabha, Lane, Lydie, Petretto, Enrico, Sobota, Radoslaw M., Jesuthasan, Suresh, Tucker-Kellogg, Lisa, Reversade, Bruno, Menschaert, Gerben, Sun, Lei, Stroud, David A., Ho, Lena
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066179/
https://ncbi.nlm.nih.gov/pubmed/32161263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14999-2
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