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Salt bridges gate α-catenin activation at intercellular junctions

Cadherin complexes transduce force fluctuations at junctions to activate signals that reinforce stressed intercellular contacts. α-Catenin is an identified force transducer within cadherin complexes that is autoinhibited under low tension. Increased force triggers a conformational change that expose...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Barrick, Samantha, Li, Jing, Kong, Xinyu, Ray, Alokananda, Tajkhorshid, Emad, Leckband, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909925/
https://ncbi.nlm.nih.gov/pubmed/29142072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-03-0168
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