Zika virus infection in immunocompetent pregnant mice causes fetal damage and placental pathology in the absence of fetal infection

Zika virus (ZIKV) infection during human pregnancy may cause diverse and serious congenital defects in the developing fetus. Previous efforts to generate animal models of human ZIKV infection and clinical symptoms often involved manipulating mice to impair their Type I interferon (IFN) signaling, th...

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Publicat a:PLoS Pathog
Autors principals: Szaba, Frank M., Tighe, Michael, Kummer, Lawrence W., Lanzer, Kathleen G., Ward, Jerrold M., Lanthier, Paula, Kim, In-Jeong, Kuki, Atsuo, Blackman, Marcia A., Thomas, Stephen J., Lin, Jr-Shiuan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909921/
https://ncbi.nlm.nih.gov/pubmed/29634758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006994
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