Zika virus infection during pregnancy in mice causes placental damage and fetal demise

Zika virus (ZIKV) infection in pregnant women causes intrauterine growth restriction, spontaneous abortion, and microcephaly. Here, we describe two mouse models of placental and fetal disease associated with in utero transmission of ZIKV. Female mice lacking type I interferon signaling (Ifnar1(−/−))...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Miner, Jonathan J., Cao, Bin, Govero, Jennifer, Smith, Amber M., Fernandez, Estefania, Cabrera, Omar H., Garber, Charise, Noll, Michelle, Klein, Robyn S., Noguchi, Kevin K., Mysorekar, Indira U., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874881/
https://ncbi.nlm.nih.gov/pubmed/27180225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.008
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