Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis

Although an essential role for canonical Notch signaling in generation of hematopoietic stem cells in the embryo and in thymic T-cell development is well established, its role in adult bone marrow (BM) myelopoiesis remains unclear. Some studies, analyzing myeloid progenitors in adult mice with inhib...

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Vydáno v:Blood
Hlavní autoři: Duarte, Sara, Woll, Petter S., Buza-Vidas, Natalija, Chin, Desmond Wai Loon, Boukarabila, Hanane, Luís, Tiago C., Stenson, Laura, Bouriez-Jones, Tiphaine, Ferry, Helen, Mead, Adam J., Atkinson, Deborah, Jin, Shaobo, Clark, Sally-Ann, Wu, Bishan, Repapi, Emmanouela, Gray, Nicki, Taylor, Stephen, Mutvei, Anders P., Tsoi, Yat Long, Nerlov, Claus, Lendahl, Urban, Jacobsen, Sten Eirik W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909886/
https://ncbi.nlm.nih.gov/pubmed/29339402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-788505
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