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An antibody targeting the fusion machinery neutralizes dual-tropic infection and defines a site of vulnerability on Epstein-Barr virus

Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis and is associated with 200,000 new cases of cancer and 140,000 deaths annually. Subunit vaccines against this pathogen have focused on the gp350 glycoprotein and remain unsuccessful. We isolated human antibodies recognizing th...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Snijder, Joost, Ortego, Michael S., Weidle, Connor, Stuart, Andrew B., Gray, Matthew D., McElrath, M. Juliana, Pancera, Marie, Veesler, David, McGuire, Andrew T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909843/
https://ncbi.nlm.nih.gov/pubmed/29669253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.03.026
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