Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations

BACKGROUND: Alterations in the composition of the lung microbiome associated with adverse clinical outcomes, known as dysbiosis, have been implicated with disease severity and exacerbations in COPD. OBJECTIVE: To characterise longitudinal changes in the lung microbiome in the AERIS study (Acute Exac...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Mayhew, David, Devos, Nathalie, Lambert, Christophe, Brown, James R, Clarke, Stuart C, Kim, Viktoriya L, Magid-Slav, Michal, Miller, Bruce E, Ostridge, Kristoffer K, Patel, Ruchi, Sathe, Ganesh, Simola, Daniel F, Staples, Karl J, Sung, Ruby, Tal-Singer, Ruth, Tuck, Andrew C, Van Horn, Stephanie, Weynants, Vincent, Williams, Nicholas P, Devaster, Jeanne-Marie, Wilkinson, Tom M A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909767/
https://ncbi.nlm.nih.gov/pubmed/29386298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2017-210408
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