Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

Lenalidomide is clinically active in chronic lymphocytic leukemia (CLL), but its effectiveness in the context of the CLL mutational landscape is unknown. We performed targeted capture sequencing of 295 cancer genes in specimens from 102 CLL patients with treatment-naïve disease (TN patients) and 186...

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發表在:Blood
Main Authors: Takahashi, Koichi, Hu, Boyu, Wang, Feng, Yan, Yuanqing, Kim, Ekaterina, Vitale, Candida, Patel, Keyur P., Strati, Paolo, Gumbs, Curtis, Little, Latasha, Tippen, Samantha, Song, Xingzhi, Zhang, Jianhua, Jain, Nitin, Thompson, Philip, Garcia-Manero, Guillermo, Kantarjian, Hagop, Estrov, Zeev, Do, Kim-Anh, Keating, Michael, Burger, Jan A., Wierda, William G., Futreal, P. Andrew, Ferrajoli, Alessandra
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2018
主題:
Lymphoid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909764/
https://ncbi.nlm.nih.gov/pubmed/29358183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-11-817296
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