Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

Lenalidomide is clinically active in chronic lymphocytic leukemia (CLL), but its effectiveness in the context of the CLL mutational landscape is unknown. We performed targeted capture sequencing of 295 cancer genes in specimens from 102 CLL patients with treatment-naïve disease (TN patients) and 186...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Takahashi, Koichi, Hu, Boyu, Wang, Feng, Yan, Yuanqing, Kim, Ekaterina, Vitale, Candida, Patel, Keyur P., Strati, Paolo, Gumbs, Curtis, Little, Latasha, Tippen, Samantha, Song, Xingzhi, Zhang, Jianhua, Jain, Nitin, Thompson, Philip, Garcia-Manero, Guillermo, Kantarjian, Hagop, Estrov, Zeev, Do, Kim-Anh, Keating, Michael, Burger, Jan A., Wierda, William G., Futreal, P. Andrew, Ferrajoli, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909764/
https://ncbi.nlm.nih.gov/pubmed/29358183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-11-817296
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