Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

Lenalidomide is clinically active in chronic lymphocytic leukemia (CLL), but its effectiveness in the context of the CLL mutational landscape is unknown. We performed targeted capture sequencing of 295 cancer genes in specimens from 102 CLL patients with treatment-naïve disease (TN patients) and 186...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Takahashi, Koichi, Hu, Boyu, Wang, Feng, Yan, Yuanqing, Kim, Ekaterina, Vitale, Candida, Patel, Keyur P., Strati, Paolo, Gumbs, Curtis, Little, Latasha, Tippen, Samantha, Song, Xingzhi, Zhang, Jianhua, Jain, Nitin, Thompson, Philip, Garcia-Manero, Guillermo, Kantarjian, Hagop, Estrov, Zeev, Do, Kim-Anh, Keating, Michael, Burger, Jan A., Wierda, William G., Futreal, P. Andrew, Ferrajoli, Alessandra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2018
Konular:
Lymphoid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909764/
https://ncbi.nlm.nih.gov/pubmed/29358183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-11-817296
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