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Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish

EZH2 is a subunit of polycomb repressive complex 2 (PRC2) that silences gene transcription via H3K27me3 and was shown to be essential for mammalian liver circadian regulation and hematopoiesis through gene silencing. Much less, however, is known about how Ezh2 acts in live zebrafish. Here, we show t...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Zhong, Yingbin, Ye, Qiang, Chen, Chengyan, Wang, Mingyong, Wang, Han
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909462/
https://ncbi.nlm.nih.gov/pubmed/29447387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky101
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