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Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish
EZH2 is a subunit of polycomb repressive complex 2 (PRC2) that silences gene transcription via H3K27me3 and was shown to be essential for mammalian liver circadian regulation and hematopoiesis through gene silencing. Much less, however, is known about how Ezh2 acts in live zebrafish. Here, we show t...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5909462/ https://ncbi.nlm.nih.gov/pubmed/29447387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky101 |
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