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Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish

EZH2 is a subunit of polycomb repressive complex 2 (PRC2) that silences gene transcription via H3K27me3 and was shown to be essential for mammalian liver circadian regulation and hematopoiesis through gene silencing. Much less, however, is known about how Ezh2 acts in live zebrafish. Here, we show t...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Zhong, Yingbin, Ye, Qiang, Chen, Chengyan, Wang, Mingyong, Wang, Han
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909462/
https://ncbi.nlm.nih.gov/pubmed/29447387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky101
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