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Ammonium and arsenic trioxide are potent facilitators of oligonucleotide function when delivered by gymnosis
Oligonucleotide (ON) concentrations employed for therapeutic applications vary widely, but in general are high enough to raise significant concerns for off target effects and cellular toxicity. However, lowering ON concentrations reduces the chances of a therapeutic response, since typically relativ...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5909461/ https://ncbi.nlm.nih.gov/pubmed/29522198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky150 |
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