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Recent Advances in Antisense Oligonucleotide Therapy in Genetic Neuromuscular Diseases

Genetic neuromuscular diseases are caused by defective expression of nuclear or mitochondrial genes. Mutant genes may reduce expression of wild-type proteins, and strategies to activate expression of the wild-type proteins might provide therapeutic benefits. Also, a toxic mutant protein may cause ce...

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Detalhes bibliográficos
Publicado no:Ann Indian Acad Neurol
Autor principal: Verma, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909143/
https://ncbi.nlm.nih.gov/pubmed/29720791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aian.AIAN_298_17
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