Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8(+) T lymphocyte proliferation

Two major phospholipase D (PLD) isozymes in mammals, PLD1 and PLD2, hydrolyze the membrane phospholipid phosphatidylcholine to choline and the lipid messenger phosphatidic acid. Although their roles in cancer cells have been well studied, their functions in tumor microenvironment have not yet been c...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Ngo Thai Bich, Van, Hongu, Tsunaki, Miura, Yuki, Katagiri, Naohiro, Ohbayashi, Norihiko, Yamashita-Kanemaru, Yumi, Shibuya, Akira, Funakoshi, Yuji, Kanaho, Yasunori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908902/
https://ncbi.nlm.nih.gov/pubmed/29674728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24512-x
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