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Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival

Pancreatic ductal adenocarcinoma (PDAC) is generally a fatal disease with no efficacious treatment modalities. Elucidation of signaling mechanisms that will lead to the identification of novel targets for therapy and chemoprevention is urgently needed. Here, we review the role of Yes-associated prot...

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Vydáno v:Signal Transduct Target Ther
Hlavní autoři: Rozengurt, Enrique, Sinnett-Smith, James, Eibl, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908807/
https://ncbi.nlm.nih.gov/pubmed/29682330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-017-0005-2
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