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KRAS, YAP, and obesity in pancreatic cancer: a signaling network with multiple loops

Pancreatic ductal adenocarcinoma (PDAC) continues to be a lethal disease with no efficacious treatment modalities. The incidence of PDAC is expected to increase, at least partially because of the obesity epidemic. Increased efforts to prevent or intercept this disease are clearly needed. Mutations i...

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Bibliografiske detaljer
Udgivet i:Semin Cancer Biol
Main Authors: Eibl, Guido, Rozengurt, Enrique
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916582/
https://ncbi.nlm.nih.gov/pubmed/29079305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.10.007
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