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KRAS, YAP, and obesity in pancreatic cancer: a signaling network with multiple loops

Pancreatic ductal adenocarcinoma (PDAC) continues to be a lethal disease with no efficacious treatment modalities. The incidence of PDAC is expected to increase, at least partially because of the obesity epidemic. Increased efforts to prevent or intercept this disease are clearly needed. Mutations i...

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Detalhes bibliográficos
Publicado no:Semin Cancer Biol
Main Authors: Eibl, Guido, Rozengurt, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916582/
https://ncbi.nlm.nih.gov/pubmed/29079305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.10.007
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