Maternal CD8(+) T cell depletion alleviates intrauterine inflammation-induced perinatal brain injury

PROBLEM: We investigated the mechanisms by which CD8(+) T cell trafficking in placenta contributes to perinatal brain injury by studying effects of maternal CD8(+) T cell depletion (DEP) in a mouse model of intrauterine inflammation (IUI). METHOD OF STUDY: Maternal CD8(+) T cells were depleted with...

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Detalhes bibliográficos
Publicado no:Am J Reprod Immunol
Main Authors: Lei, Jun, Xie, Li, Zhao, Hongxi, Gard, Candice, Clemens, Julia L., McLane, Michael W., Feller, Mia C., Ozen, Maide, Novak, Christopher, Alshehri, Wael, Alhejaily, Nader, Shabi, Yahya, Rosenzweig, Jason M., Facciabene, Andrea, Burd, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908745/
https://ncbi.nlm.nih.gov/pubmed/29205631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12798
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