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Imaging markers of response to combined BRAF and MEK inhibition in BRAF mutated vemurafenib-sensitive and resistant melanomas

A majority of patients with a V600x melanoma respond quickly to BRAF/MEK inhibition (BRAFi/MEKi) and have an obvious clinical benefit. Nearly all the patients after this initial phase will develop resistance. Therefore, non-invasive early markers of response/non-response are needed in order to ident...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Acciardo, Stefania, Mignion, Lionel, Joudiou, Nicolas, Bouzin, Caroline, Baurain, Jean-François, Gallez, Bernard, Jordan, Bénédicte F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908289/
https://ncbi.nlm.nih.gov/pubmed/29682188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24709
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